Interaction of simulation and test for the statistical validation of virtual product development
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Pharmacophore Based Virtual Screening Approach to Identify Selective PDE4B Inhibitors
Phosphodiesterase 4 (PDE4) has been established as a promising target in asthma andchronic obstructive pulmonary disease. PDE4B subtype selective inhibitors are known toreduce the dose limiting adverse effect associated with non-selective PDE4B inhibitors. Thismakes the development of PDE4B subtype selective inhibitors a desirable research goal. Toachieve this goal, ligand based pharmacophore m...
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Although there are many potential benefits associated with the use of virtual product development teams, exploiting these benefits requires an appropriate management. Managing virtual product development team is a critical issue as many of these teams fail to accomplish their goals. Review of previous literature shows that body of knowledge in managing virtual product development teams is fragm...
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Phosphodiesterase 4 (PDE4) has been established as a promising target in asthma andchronic obstructive pulmonary disease. PDE4B subtype selective inhibitors are known toreduce the dose limiting adverse effect associated with non-selective PDE4B inhibitors. Thismakes the development of PDE4B subtype selective inhibitors a desirable research goal. Toachieve this goal, ligand based pharmacophore m...
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The main problem is less efficiency and blocking during sugarcane harvesting in hilly areas. This paper researched the cutting and transporting system of a small sugarcane harvester using virtual prototype technology. The dynamics simulation analyses were carried out to study the transporting status with different friction coefficients between the sugarcane and the spiral and different numbers ...
متن کاملDevelopment and Validation of An Instrument for Determining Knowledge and Practice of Pistachio Farmers in Terms of Aflatoxin and the Prevention Methods of its Production in Pistachio Product
Background and Objective: Given the necessity of assessing knowledge and practice of individuals to prevent the Aflatoxin contamination in pistachio in order to develop appropriate educational interventions, design and validating a standard tool is essential. Therefore, the purpose of this study was to develop and validate an instrument to determine the knowledge and performance of pistachio fa...
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